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YM17E
$543
Only 1000 item(s) left in stock.
Products Details
Product Description
– YM17E is an inhibitor of acyl CoA:cholesterol acyltransferase (ACAT), with IC50 of 44 nM in rabbit liver microsomes in vitro.
Web ID
– HY-101627
Storage Temperature
– -20°C, 3 years (Powder)
Shipping
– Blue Ice
Applications
– Metabolism-sugar/lipid metabolism
Molecular Formula
– C40H56N6O2
References
– [1]Uchida T, et al. Relationship between bioavailability and hypocholesterolemic activity of YM17E, an inhibitor of ACAT, in cholesterol-fed rats. Atherosclerosis. 1998 Mar;137(1):97-106.|[2]Kashiwa M, et al. Pharmacological properties of YM17E, an acyl-CoA:cholesterol acyltransferase inhibitor, and diarrheal effect in beagle dogs. Jpn J Pharmacol. 1997 Jan;73(1):41-50.
CAS Number
– 124900-72-7
Molecular Weight
– 652.91
Compound Purity
– 98.34
SMILES
– O=C(NC1=CC=C(N(C)C)C=C1)N(CC2=CC=CC(CN(C3CCCCCC3)C(NC4=CC=C(N(C)C)C=C4)=O)=C2)C5CCCCCC5
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– DMSO : ≥ 125 mg/mL
Target
– Acyltransferase
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
