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YM-58790
$390 – $3,250
Products Details
Product Description
– YM-58790 is a potent antagonist of mAChR. YM-58790 binds M1, M2, M3 with Ki values of 28 nM, 260 nM, and 15 nM. YM-58790 exhibits potent inhibitory activity on bladder pressuer in reflexly-evoked rhythmic contraction in rats[1].
Web ID
– HY-101679
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C27H32ClN3O2
References
– [1]Naito R, et al. Selective muscarinic antagonists. I. Synthesis and antimuscarinic properties of 4-piperidyl benzhydrylcarbamate derivatives. Chem Pharm Bull (Tokyo). 1998 Aug;46(8):1274-85.
CAS Number
– 214558-72-2
Molecular Weight
– 466.01
Compound Purity
– 98.21
SMILES
– O=C(OC1CCN(CC2=CC=C(NC)C=C2)CC1)NC(C3=CC=CC=C3)C4=CC=CC=C4.[H]Cl
Clinical Information
– Phase 1
Research Area
– Neurological Disease
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– mAChR
Isoform
– mAChR1;mAChR2;mAChR3
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
