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Products Details
Product Description
– YM-08 (Compounds 7a) is a brain-penetrant inhibitors of SIRT2,with the IC50 of 19.9 μM. YM-08 also is inhibitor of Hsp70[1].
Web ID
– HY-139144
Shipping
– Room temperature
Molecular Formula
– C19H17N3OS2
References
– [1]Abbotto E, et al. Novel Thiazole-Based SIRT2 Inhibitors Discovered via Molecular Modelling Studies and Enzymatic Assays. Pharmaceuticals (Basel). 2023;16(9):1316. Published 2023 Sep 18.
CAS Number
– 812647-88-4
Molecular Weight
– 367.49
SMILES
– O=C1N(CC)/C(S/C1=C2SC3=CC=CC=C3N/2C)=CC4=NC=CC=C4
Clinical Information
– No Development Reported
Research Area
– Cancer; Neurological Disease
Solubility
– 10 mM in DMSO
Target
– HSP;Sirtuin
Isoform
– HSP70
Pathway
– Cell Cycle/DNA Damage;Epigenetics;Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
