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Products Details
Product Description
– YG1702 is a potent ALDH18A1-specific inhibitor. YG1702 attenuates the growth of MYCN-amplified NB and down-regulates MYCN. YG1702 physically interacts with ALDH18A1 with a high affinity and might potentially affect its enzymatic activity[1].
Web ID
– HY-156443
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C23H30N2O7S
References
– [1]Guo YF, et al. Inhibition of the ALDH18A1-MYCN positive feedback loop attenuates MYCN-amplified neuroblastoma growth. Sci Transl Med. 2020 Feb 19;12(531):eaax8694.
CAS Number
– 724737-08-0
Molecular Weight
– 478.56
SMILES
– O=C(C1=C(C)NC(C)=C(C1C2=C([N+]([O-])=O)C=CC=C2)C(OCCSC(C)C)=O)OCCOC
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Aldehyde Dehydrogenase (ALDH)
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
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