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YAP-TEAD-IN-2
$1,300 – $4,600
Products Details
Product Description
– YAP-TEAD-IN-2 (compound 6) is a potent YAP-TEAD PPI (protein-protein interaction) inhibitor, with an IC50 of 2.7 nM[1].
Web ID
– HY-151525
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C25H24ClFN2O4
References
– [1]Furet P, et al. The First Class of Small Molecules Potently Disrupting the YAP-TEAD Interaction by Direct Competition. ChemMedChem. 2022 Oct 6;17(19):e202200303.
CAS Number
– 2714432-83-2
Molecular Weight
– 470.92
SMILES
– NC[C@]1(CC2=[C@@](C(Cl)=CC=C2O1)[C@@]3=C(C(N)=O)C=CC(OCCOC)=C3F)C4=CC=CC=C4
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– H2O
Target
– YAP
Pathway
– Stem Cell/Wnt
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
