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Products Details
Product Description
– Y08175 is a potent CBP bromodomain inhibitor. Y08175 exhibits considerable inhibitory effect with IC50s of 37 and 178.15 nM against CBP bromodomain in AlphaScreen assay and HTRF assay, respectively. Y08175 can be used for the research of prostate cancer[1].
Web ID
– HY-142743
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C23H19FN4O5
References
– [1]Xiang Q, et al. Design, Synthesis, and Biological Evaluation of 1-(Indolizin-3-yl)ethan-1-ones as CBP Bromodomain Inhibitors for the Treatment of Prostate Cancer. J Med Chem. 2022;65(1):785-810.
CAS Number
– 2223014-57-9
Molecular Weight
– 450.42
SMILES
– O=C(O)C1=CC(C2=CN(C)N=C2)=C(F)C(NC(C3=CN(C(C)=O)C4=C3C=C(OC)C=C4)=O)=C1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Epigenetic Reader Domain
Pathway
– Epigenetics
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
