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Products Details
Product Description
– XS-060 is a potent anticancer agent and RXRα antagonist. XS-060 significantly induces RXRα-dependent mitotic arrest by inhibiting pRXRα-PLK1 interaction[1].
Web ID
– HY-149085
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C20H18N2O3
References
– [1]Chen J, et al. Discovery of bipyridine amide derivatives targeting pRXRα-PLK1 interaction for anticancer therapy. Eur J Med Chem. 2023 Apr 6;254:115341.
CAS Number
– 2787626-06-4
Molecular Weight
– 334.37
SMILES
– COC(C=C1)=CC=C1CC(N/N=C/C2=C(O)C=CC3=C2C=CC=C3)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– RAR/RXR
Pathway
– Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor
Product type
– Reference compound
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