XL177A

SKU HY-138794-1 mg Category Tags , ,

$123$1,940

Products Details

Product Description

– XL177A is a highly potent and selective irreversible USP7 inhibitor with an IC50 of 0.34 nM. XL177A elicits cancer cell killing through a p53-dependent mechanism[1].

Web ID

– HY-138794

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C48H57ClN8O5

References

– [1]Nathan J Schauer, et al. Selective USP7 inhibition elicits cancer cell killing through a p53-dependent mechanism. Sci Rep.2020 Mar 24;10(1):5324.

CAS Number

– 2417089-74-6

Molecular Weight

– 861.47

Compound Purity

– 98.63

SMILES

– O=C(C(C=CC1=C2Cl)=CC1=NC3=C2CCCC3)NCCC[C@@H](CC4=CC=CC=C4)C(N5CCC(CN6C=NC7=C(C=CC(NC(CCN8CCN(C)CC8)=O)=C7)C6=O)(O)CC5)=O

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– DMSO : 25 mg/mL (ultrasonic)

Target

– Deubiquitinase

Pathway

– Cell Cycle/DNA Damage

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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