XL 188

SKU HY-122886-1 mg Category Tags , ,

$40$870

Products Details

Product Description

– XL 188 is a potent and selective USP7 inhibitor with IC50 values of 90 nM and 193 nM for USP7 full-length and catalytic domain enzyme, respectively. XL 188 can be used in research of cancer[1].

Web ID

– HY-122886

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Molecular Formula

– C32H42N6O4

References

– [1]Stolte B, et, al. Genome-scale CRISPR-Cas9 screen identifies druggable dependencies in TP53 wild-type Ewing sarcoma. J Exp Med. 2018 Aug 6;215(8):2137-2155.

CAS Number

– 2305045-76-3

Molecular Weight

– 574.71

Compound Purity

– 98.00

SMILES

– O=C(NC1=CC(N=CN2CC3(O)CCN(C(C[C@H](C4=CC=CC=C4)C)=O)CC3)=C(C=C1)C2=O)CCN5CCN(C)CC5

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– DMSO : 100 mg/mL (ultrasonic)

Target

– Deubiquitinase

Pathway

– Cell Cycle/DNA Damage

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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