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Product Description
– XIAP BIR2/BIR2-3 inhibitor-3 is a dual inhibitor of BIR2 and BIR2-3 with IC50s less than 1 nM. XIAP BIR2/BIR2-3 inhibitor-3 can used in study cancers[1].
Web ID
– HY-160030
Shipping
– Room temperature
Molecular Formula
– C86H106N18O16S2
References
– [1]Benjamin Adam Seigal, et al. Macrocyclic compounds for inhibition of inhibitors of apoptosis. EP2776409B1. 2014-09-17.
CAS Number
– 1434125-52-6
Molecular Weight
– 1712.00
SMILES
– CN[C@@H](C)C(N[C@@H](C(C)(C)C)C(N1[C@@]2([H])C[C@@](N3C=C(COC4=CC=C(C[C@H](NC([C@@H](NC([C@]5([H])C[C@](CN5C([C@H](C(C)(C)C)NC([C@H](C)NC)=O)=O)([H])N6C=C(N=N6)COC7=CC=C(C[C@H](NC([C@@H](NC2=O)CC8=CC=CC9=C8C=CC=C9)=O)C(NS(=O)(C%10CC%10)=O)=O)C=C7)=O)CC%11=CC=CC%12=C%11C=CC=C%12)=O)C(NS(=O)(C%13CC%13)=O)=O)C=C4)N=N3)([H])C1)=O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– IAP
Pathway
– Apoptosis
Product type
– Reference compound
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