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Products Details
Product Description
– XIAP BIR2/BIR2-3 inhibitor-1 (compound 3) is a dual inhibitor of BIR2 and BIR2-3 with IC50s of 1.9 and 0.8 nM, respectively. XIAP BIR2/BIR2-3 inhibitor-1 can used in study cancers[1].
Web ID
– HY-160022
Shipping
– Room temperature
Molecular Formula
– C72H96N16O14
References
– [1]Robert M. Borzilleri, et al. Macrocyclic compounds for inhibition of inhibitors of apoptosis. WO2014074665A1. 2014-05-15.
CAS Number
– 1609384-59-9
Molecular Weight
– 1409.63
SMILES
– O=C(N1[C@@](C(N[C@H](C(N[C@H](CCCN2C=C(CO[C@@](CCN3C([C@H](C(C)(C)C)NC([C@H](C)NC)=O)=O)([H])[C@@]3([H])C4=O)N=N2)C(O)=O)=O)CC5=CC(C=CC=C6)=C6C=C5)=O)([H])[C@@](OCC7=CN(CCC[C@@H](NC([C@@H](N4)CC8=CC(C=CC=C9)=C9C=C8)=O)C(O)=O)N=N7)([H])CC1)[C@H](C(C)(C)C)NC([C@H](C)NC)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– IAP
Pathway
– Apoptosis
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
