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Xeruborbactam (disodium)
$1,650 – $7,500
Products Details
Product Description
– Xeruborbactam (QPX7728) disodium is a potent, ultra-broad-spectrum boronic acid beta-lactamase inhibitor. Xeruborbactam disodium inhibits key serine and metallo beta-lactamases at a nano molar range[1].
Web ID
– HY-136072
Storage Temperature
– -20°C (Powder, sealed storage, away from moisture and light)
Shipping
– Blue Ice
Applications
– COVID-19-immunoregulation
Molecular Formula
– C10H8BFNa2O5
References
– [1]Lomovskaya O, et al, The Impact of Intrinsic Resistance Mechanisms on Potency of QPX7728, a New Ultra-Broad-Spectrum Beta-lactamase Inhibitor of Serine and Metallo Beta-Lactamases in Enterobacteriaceae, Pseudomonas aeruginosa, and Acinetobacter baumannii. Antimicrob Agents Chemother. 2020 Mar 30. pii: AAC.00552-20.|[2]Hecker SJ, Reddy KR, Lomovskaya O, et al. Discovery of Cyclic Boronic Acid QPX7728, an Ultrabroad-Spectrum Inhibitor of Serine and Metallo-β-lactamases. J Med Chem. 2020;63(14):7491-7507.
CAS Number
– 2170848-99-2
Molecular Weight
– 283.96
Compound Purity
– 99.85
SMILES
– O[B-](O1)(O)[C@@H]2C[C@@H]2C3=C1C(C(O[Na])=O)=C(C=C3)F.[Na+]
Clinical Information
– Phase 1
Research Area
– Infection
Solubility
– DMSO : 100 mg/mL (ultrasonic)|H2O : 76.67 mg/mL (ultrasonic)
Target
– Bacterial
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
