Download Files:
WW437
SKU
HY-143654-Get quote
Category Reference compound
Tags Cancer, Cell Cycle/DNA Damage;Epigenetics, HDAC
Products Details
Product Description
– WW437 is a histone deacetylase (HDAC) inhibitor with potent anti-breast cancer ability in vitro and in vivo.
Web ID
– HY-143654
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C23H27N5O4
References
– [1]Zhang T, et al. Inhibition of HDACs-EphA2 Signaling Axis with WW437 Demonstrates Promising Preclinical Antitumor Activity in Breast Cancer. EBioMedicine. 2018 May;31:276-286.
Molecular Weight
– 437.49
SMILES
– COC1=CC=C(C=C1)N(C(CCCCCC(NO)=O)=O)CC2=CN(N=N2)C3=CC=CC=C3
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– HDAC
Pathway
– Cell Cycle/DNA Damage;Epigenetics
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.