Products Details

Product Description

– WRN inhibitor 2 (example 118) is a WRN (Werner Syndrome ATP dependent helicase enzyme) inhibitor, with pIC50 ≥ 7.0[1].

Web ID

– HY-153973

Shipping

– Room temperature

Molecular Formula

– C15H11F3N2O5S2

References

– [1]Ashley ADAMS, et al. Cyclic vinyl sulfone compounds as wrn inhibitors. Patent, WO2023062575A1.

CAS Number

– 2923009-56-5

Molecular Weight

– 420.38

SMILES

– OC1=C(NC(C(C(N[C@@H]2C=CS(=O)(C2)=O)=O)=C1)=O)C3=CSC(C(F)(F)F)=C3

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– DNA/RNA Synthesis

Pathway

– Cell Cycle/DNA Damage

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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