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Products Details
Product Description
– WRN inhibitor 2 (example 118) is a WRN (Werner Syndrome ATP dependent helicase enzyme) inhibitor, with pIC50 ≥ 7.0[1].
Web ID
– HY-153973
Shipping
– Room temperature
Molecular Formula
– C15H11F3N2O5S2
References
– [1]Ashley ADAMS, et al. Cyclic vinyl sulfone compounds as wrn inhibitors. Patent, WO2023062575A1.
CAS Number
– 2923009-56-5
Molecular Weight
– 420.38
SMILES
– OC1=C(NC(C(C(N[C@@H]2C=CS(=O)(C2)=O)=O)=C1)=O)C3=CSC(C(F)(F)F)=C3
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– DNA/RNA Synthesis
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
