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WNK-IN-11-d3
SKU
HY-112094S-10 mg
Category Isotope-Labeled Compounds
Tags Cardiovascular Disease, Metabolic Enzyme/Protease, Ser/Thr Protease
$750 – $5,800
Products Details
Product Description
– WNK-IN-11-d3 is an orally active, selective and potent With-No-Lysine (WNK) kinase inhibitor. WNK-IN-11-d3 is effective at regulating cardiovascular homeostasis[1].
Web ID
– HY-112094S
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C21H18D3Cl2N5OS
References
– [1]Yamada K, Levell J, Yoon T, et al. Optimization of Allosteric With-No-Lysine (WNK) Kinase Inhibitors and Efficacy in Rodent Hypertension Models. J Med Chem. 2017;60(16):7099-7107.
CAS Number
– 2123483-49-6
Molecular Weight
– 465.41
Compound Purity
– 99.84
SMILES
– O=C(N1CCN(CC1)CC2=CC=C(C=C2)Cl)C3=CC(C4=CSC(NC([2H])([2H])[2H])=N4)=NC=C3Cl
Clinical Information
– No Development Reported
Research Area
– Cardiovascular Disease
Solubility
– DMSO : ≥ 100 mg/mL
Target
– Ser/Thr Protease
Pathway
– Metabolic Enzyme/Protease
Product type
– Isotope-Labeled Compounds
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.