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Products Details
Product Description
– WF-536 is an orally active inhibitor of Rho-associated coiled-coil-containing protein kinase (ROCK). WF-536 has tumor anti-metastatic activity. WF-536 can be used for the research of cancer[1].
Web ID
– HY-118837
Shipping
– Room temperature
Molecular Formula
– C14H16ClN3O
References
– [1]Nakajima, Masahide et al. Wf-536 prevents tumor metastasis by inhibiting both tumor motility and angiogenic actions. European journal of pharmacology vol. 459,2-3 (2003): 113-20.
CAS Number
– 539857-64-2
Molecular Weight
– 277.75
SMILES
– O=C(C1=CC=C(C=C1)[C@@H](C)N)NC2=CC=NC=C2.Cl
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– ROCK
Pathway
– Cell Cycle/DNA Damage;Cytoskeleton;Stem Cell/Wnt;TGF-beta/Smad
Product type
– Reference compound
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