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Products Details
Product Description
– WES-1 (Compound 8g) is an inhibitor of carbonic anhydrase IX (Ki: 55.9 μM). WES-1 has broad spectrum anti-proliferative activity against the cancer cells, such as leukemia (K-562 and MOLT-4), non-small cell lung cancer (NCI–H460), colon cancer (HCT 116 and HCT-15) and melanoma (LOX IMVI) cell lines[1].
Web ID
– HY-155522
Shipping
– Room temperature
Molecular Formula
– C20H20N4O3S
References
– [1]Eldehna WM, et al. Design and synthesis of 6-arylpyridine-tethered sulfonamides as novel selective inhibitors of carbonic anhydrase IX with promising antitumor features toward the human colorectal cancer. Eur J Med Chem. 2023 Oct 5;258:115538.
CAS Number
– 2748673-86-9
Molecular Weight
– 396.46
SMILES
– O=C(NC1=C(S(=O)(N)=O)C=CC=C1)NC2=CC=C(C3=CC=C(C)C=C3)N=C2C
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Carbonic Anhydrase
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
