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Products Details
Product Description
– VUF10497 is a potent histamine H4 receptor (H4R) inverse agonist with anti-inflammatory activity[1].
Web ID
– HY-118336
Shipping
– Room temperature
Molecular Formula
– C18H20ClN5S
References
– [1]Smits RA, et al. Discovery of quinazolines as histamine H4 receptor inverse agonists using a scaffold hopping approach. J Med Chem. 2008 Dec 25;51(24):7855-65.
CAS Number
– 1080623-12-6
Molecular Weight
– 373.90
SMILES
– CN1CCN(CC1)C2=NC(NCC3=CC=CS3)=C4C=C(C=CC4=N2)Cl
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Histamine Receptor
Pathway
– GPCR/G Protein;Immunology/Inflammation;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
