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VU6036720 (hydrochloride)
SKU
HY-148304A-10 mg
Category Reference compound
Tags Cancer; Metabolic Disease; Inflammation/Immunology, Membrane Transporter/Ion Channel, Potassium Channel
$300 – $2,250
Products Details
Product Description
– VU6036720 hydrochloride is a potent and specific in vitro inhibitor of Kir4.1/5.1. VU6036720 hydrochloride can inhibit Kir4.1/5.1 channels with an IC50 value of 0.24 μM. VU6036720 hydrochloride can be used for the research of brain and kidney[1].
Web ID
– HY-148304A
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture and light)
Shipping
– Room Temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C20H23Cl2FN4O2S
References
– [1]Samantha J McClenahan, et al. VU6036720: The First Potent and Selective In Vitro Inhibitor of Heteromeric Kir4.1/5.1 Inward Rectifier Potassium Channels. Mol Pharmacol. 2022 May;101(5):357-370.
Molecular Weight
– 473.39
Compound Purity
– 99.52
SMILES
– C[C@H]1CN(CCN1CCNS(=O)(C2=CC(Cl)=C(C=C2)F)=O)C3=C(C#N)C=CC=C3.[H]Cl
Clinical Information
– No Development Reported
Research Area
– Cancer; Metabolic Disease; Inflammation/Immunology
Solubility
– DMSO : 40 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– Potassium Channel
Pathway
– Membrane Transporter/Ion Channel
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.