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Products Details
Product Description
– VU0455691 is a potent, selective orthosteric M1 mAChR antagonist (pIC50=6.64; IC50=0.23 µM for hM1)[1].
Web ID
– HY-116569
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C24H25N5O3S
References
– [1]Melancon BJ, et al. Development of novel M1 antagonist scaffolds through the continued optimization of the MLPCN probe ML012. Bioorg Med Chem Lett. 2012;22(15):5035-5040.
CAS Number
– 1392443-41-2
Molecular Weight
– 463.55
SMILES
– O=C(C1CN(C1)S(=O)(C2=CC=CC3=C2C=CN=C3)=O)N4CC5CN(CC5C4)C6=CC=NC=C6
Clinical Information
– No Development Reported
Research Area
– Cardiovascular Disease
Solubility
– 10 mM in DMSO
Target
– mAChR
Isoform
– mAChR1
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
