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VU0405601
$283 – $814
Products Details
Product Description
– VU0405601 is a potent KV11.1 channel activator. VU0405601 protects cardiac tissue from Dofetilide (HY-B0232)-induced ventricular tachycardia[1][2].
Web ID
– HY-116759
Shipping
– Room temperature
Molecular Formula
– C17H13BrN2O2
References
– [1]Egly CL, et al. A High-Throughput Screening Assay to Identify Drugs that Can Treat Long QT Syndrome Caused by Trafficking-Deficient KV11.1 (hERG) Variants. Mol Pharmacol. 2022 Apr;101(4):236-245. |[2]Potet F, et al. Identification and characterization of a compound that protects cardiac tissue from human Ether-à-go-go-related gene (hERG)-related drug-induced arrhythmias. J Biol Chem. 2012 Nov 16;287(47):39613-25.
CAS Number
– 712325-30-9
Molecular Weight
– 357.20
SMILES
– O=C(COC1=CC=C2C=CC=CC2=C1Br)NC3=CC=CN=C3
Clinical Information
– No Development Reported
Research Area
– Cardiovascular Disease
Solubility
– 10 mM in DMSO
Target
– Potassium Channel
Pathway
– Membrane Transporter/Ion Channel
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
