VK-1727

$360$1,450

Products Details

Product Description

– VK-1727 is a selective small molecule inhibitor of EBNA1. VK-1727 can reduce EBNA1 DNA binding activity. VK-1727 selectively blocks the proliferation and metabolic activity of EBV+ cells, instead of EBV- cells. VK-1727 is used in multiple sclerosis research[1].

Web ID

– HY-125471

Shipping

– Room temperature

Molecular Formula

– C29H25NO4

References

– [1]Monaco MCG, et al. EBNA1 Inhibitors Block Proliferation of Spontaneous Lymphoblastoid Cell Lines From Patients With Multiple Sclerosis and Healthy Controls. Neurol Neuroimmunol Neuroinflamm. 2023 Aug 10;10(5):e200149.

Molecular Weight

– 451.51

SMILES

– O=C(OC)C1=CC=CC(C#CC2=CC=C(OC3CCOCC3)C=C2)=C1C4=CC5=C(C=C4)C=CN5

Clinical Information

– No Development Reported

Research Area

– Cancer; Infection; Inflammation/Immunology

Solubility

– 10 mM in DMSO

Target

– EBV

Pathway

– Anti-infection

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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