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Product Description
– Vin-F03 is a potent pancreatic β-cells protective agent with an EC50 of 0.27 µM. Vin-F03 effectively promotes β-cell survival and protects β-cells from STZ-induced apoptosis. Vin-F03 can be used for type 2 diabetes mellitus research[1].
Web ID
– HY-147503
Shipping
– Room temperature
Applications
– Neuroscience-Neurodegeneration
Molecular Formula
– C22H29N3
References
– [1]Wang J, et al. Design, synthesis and biological evaluation of vincamine derivatives as potential pancreatic β-cells protective agents for the treatment of type 2 diabetes mellitus. Eur J Med Chem. 2020 Feb 15;188:111976.
CAS Number
– 2180917-11-5
Molecular Weight
– 335.49
SMILES
– [H][C@]12C3=C4CCN1CCC[C@]2(C=C(N3C5=CC=CC=C54)CNCC)CC
Clinical Information
– No Development Reported
Research Area
– Cardiovascular Disease
Solubility
– 10 mM in DMSO
Target
– Apoptosis
Pathway
– Apoptosis
Product type
– Reference compound
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