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VH032-C2-NH-Boc
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Products Details
Product Description
– VH032-C2-NH-Boc is a Boc-modified VH032 (HY-120217) that acts as a ligand for VHL and recruits von Hippel-Lindau (VHL) proteins. VH032-C2-NH-Boc will remove the protecting group under acidic conditions, and can be directly used for the synthesis of PROTAC molecules. VH032-C2-NH-Boc is a key intermediate for the synthesis of PROTACs based on VHL ligands.
Web ID
– HY-W584529
Shipping
– Room temperature
Molecular Formula
– C31H45N5O6S
CAS Number
– 2361119-87-9
Molecular Weight
– 615.78
SMILES
– O=C(NCC1=CC=C(C2=C(C)N=CS2)C=C1)[C@H]3N(C([C@H](C(C)(C)C)NC(CCCNC(OC(C)(C)C)=O)=O)=O)C[C@H](O)C3
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Ligands for E3 Ligase
Pathway
– PROTAC
Product type
– Reference compound
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