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VH032 analogue-1
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Products Details
Product Description
– VH032 analogue-1 is a VH032 (HY-120217) analog that acts as a ligand for VHL, recruiting von Hippel-Lindau (VHL) protein. VH032 analogue-1 will remove the protective group under acidic conditions and be directly used for PROTAC molecular synthesis. VH032 analogue-1 is a key intermediate in the synthesis of PROTACs based on VHL ligands.
Web ID
– HY-W584527
Shipping
– Room temperature
Molecular Formula
– C23H30N4O5S
CAS Number
– 2111829-84-4
Molecular Weight
– 474.57
SMILES
– CC(N=CS1)=C1C(C=C2)=CC=C2CNC([C@H]3N(C[C@@H](C3)O)C(CNC(OC(C)(C)C)=O)=O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Ligands for E3 Ligase
Pathway
– PROTAC
Product type
– Reference compound
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