Verapamil EP Impurity C (hydrochloride)

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Products Details

Product Description

– NSC-609249 hydrochloride is an impurity of Verapamil (HY-14275). Verapamil is a calcium channel blocker and a potent and orally active first-generation P-glycoprotein (P-gp) inhibitor[1][2].

Web ID

– HY-136589

Storage Temperature

– 4°C (Powder, sealed storage, away from moisture)

Shipping

– Room Temperature

Applications

– Metabolism-sugar/lipid metabolism

Molecular Formula

– C12H20ClNO2

References

– [1]Gowarty JL, et al. Verapamil as a culprit of palbociclib toxicity. J Oncol Pharm Pract. 2019 Apr;25(3):743-746.|[2]Krikler DM. Verapamil in arrhythmia. Br J Clin Pharmacol. 1986;21 Suppl 2:183S-189S.

CAS Number

– 51012-67-0

Molecular Weight

– 245.75

Compound Purity

– 99.61

SMILES

– CN(C)CCC1=CC=C(OC)C(OC)=C1.[H]Cl

Clinical Information

– No Development Reported

Research Area

– Metabolic Disease

Solubility

– DMSO : 62.5 mg/mL (ultrasonic;warming;heat to 60°C)

Target

– Calcium Channel;Cytochrome P450;P-glycoprotein

Pathway

– Membrane Transporter/Ion Channel;Metabolic Enzyme/Protease;Neuronal Signaling

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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