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VER-50589

$60$250

Products Details

Product Description

– VER-50589 is a Hsp90 inhibitor, with an IC50 of 21 nM and a Kd of 4.5 nM.

Web ID

– HY-15984

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C19H17ClN2O5

References

– [1]Sharp SY, et al. Inhibition of the heat shock protein 90 molecular chaperone in vitro and in vivo by novel, synthetic, potent resorcinylic pyrazole/isoxazole amide analogues. Mol Cancer Ther. 2007 Apr;6(4):1198-211.

CAS Number

– 747413-08-7

Molecular Weight

– 388.80

Compound Purity

– 99.97

SMILES

– O=C(C1=NOC(C2=CC(Cl)=C(O)C=C2O)=C1C3=CC=C(OC)C=C3)NCC

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– DMSO : ≥ 48 mg/mL

Target

– Apoptosis;HSP

Isoform

– HSP90

Pathway

– Apoptosis;Cell Cycle/DNA Damage;Metabolic Enzyme/Protease

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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