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Products Details
Product Description
– VER-00158411 is a checkpoint kinase 1 (CHK1) and CHK2 inhibitor with IC50 values of 4.4 nM and 4.5 nM, respectively[1].
Web ID
– HY-18942
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C31H34N6O3
References
– [1] Ann Gee Lisa OOI, et al. Combination therapy. 26 July 2018. WO2018136010A1
CAS Number
– 1174664-88-0
Molecular Weight
– 538.64
SMILES
– O=C(C1=CN(CC2=CC=CC=C2)N=C1)NC(C=C3C(N4)=CC5=C4C=CC(OCC(C)(C)CN(C)C)=C5)=CNC3=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Checkpoint Kinase (Chk)
Isoform
– Chk1;Chk2
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
