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Products Details
Product Description
– VEGFR2-IN-4 (compound 25) is a potent and selective VEGFR2 kinase inhibitor, with a GI50 of 0.7 nM. VEGFR2-IN-4 shows anti-angiogenic effect. VEGFR2-IN-4 can be used for the research of rheumatoid arthritis[1].
Web ID
– HY-149361
Shipping
– Room temperature
Molecular Formula
– C23H20N4O3S
References
– [1]Chen Q, et, al. Discovery of highly potent and selective VEGFR2 kinase inhibitors for the treatment of rheumatoid arthritis. Eur J Med Chem. 2023 Sep 5;257:115456.
Molecular Weight
– 432.49
SMILES
– O=C(C1=CC(OC)=CC=C1)NC2=CC(SC3=CC=C4C(NN=C4NC(C)=O)=C3)=CC=C2
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– VEGFR
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
