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Products Details
Product Description
– VEGFR-IN-3 (compound 3f) is a VEGFR inhibitor. VEGFR-IN-3 inhibits OVCAR-4 and MDA-MB-468 cancer cells growth with IC50s of 0.29 and 0.35 μM, respectively. VEGFR-IN-3 can be used for the research of cancer[1].
Web ID
– HY-143293
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C27H28N2O6
References
– [1]Hassan RA, et al. Design, synthesis and evaluation of anticancer activity of new pyrazoline derivatives by down-regulation of VEGF: Molecular docking and apoptosis inducing activity. Bioorg Chem. 2022 Jan;118:105487.
CAS Number
– 2874264-13-6
Molecular Weight
– 476.52
SMILES
– CC(N(C(C1)C2=CC=C(C=C2)OC3=CC=C(C=C3)OC)N=C1C4=CC(OC)=C(OC)C(OC)=C4)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Apoptosis;VEGFR
Pathway
– Apoptosis;Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
