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VEGFR-IN-1
$55 – $265
Products Details
Product Description
– VEGFR-IN-1 (compound 3) is a potent angiogenesis inhibitor with IC50s of 0.02, 0.18, 0.24 7.3, and 7 µM for KDR, Flt-1, c-Kit, EGF-R, and c-Src, respectively[1].
Web ID
– HY-101219
Storage Temperature
– -20°C (Powder, protect from light, stored under nitrogen)
Shipping
– Blue Ice
Applications
– Cancer-Kinase/protease
Molecular Formula
– C19H16ClN3O
References
– [1]Furet P, et al. Identification of a new chemical class of potent angiogenesis inhibitors based on conformational considerations and database searching. Bioorg Med Chem Lett. 2003;13(18):2967-2971.
CAS Number
– 269390-69-4
Molecular Weight
– 337.80
Compound Purity
– 98.42
SMILES
– O=C(NC1=CC=C(Cl)C=C1)C2=CC=CC=C2NCC3=CC=NC=C3
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 125 mg/mL (ultrasonic)
Target
– c-Kit;EGFR;VEGFR
Isoform
– EGFR/ErbB1/HER1;VEGFR1/Flt-1;VEGFR2/KDR/Flk-1
Pathway
– JAK/STAT Signaling;Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
