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Products Details
Product Description
– VEGFR-2-IN-35 (compound 7) is a potent VEGFR-2 inhibitor with IC50=37 nM. VEGFR-2-IN-35 inhibits MCF-7 and HCT 116 cancer cells with IC50 values of 10.56 and 7.07 μM, respectively[1].
Web ID
– HY-155239
Shipping
– Room temperature
Molecular Formula
– C25H19N3O3
References
– [1]Elkaeed EB, et al. In silico, in vitro VEGFR-2 inhibition, and anticancer activity of a 3-(hydrazonomethyl)naphthalene-2-ol derivative. J Biomol Struct Dyn. 2023 Sep-Oct;41(16):7986-8001.. .
Molecular Weight
– 409.44
SMILES
– O=C(C1=CC=C(NC(C2=CC=CC=C2)=O)C=C1)N/N=C/C3=CC(C=CC=C4)=C4C=C3O
Clinical Information
– No Development Reported
Research Area
– cancer
Solubility
– 10 mM in DMSO
Target
– VEGFR
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
