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Products Details
Product Description
– VEGFR-2-IN-33 (Compound 4d) is a VEGFR inhibitor (IC50: 61.04 nM). VEGFR-2-IN-33 inhibits HepG2 cell proliferation with an IC50 of 4.31 nM. VEGFR-2-IN-33 can be used for research of hepatocellular carcinoma (HCC)[1].
Web ID
– HY-149475
Shipping
– Room temperature
Molecular Formula
– C20H14N6O2S2
References
– [1]El-Hazek RMM, et al. Novel VEGFR2 inhibitors with thiazoloquinoxaline scaffold targeting hepatocellular carcinoma with lower cardiotoxic impact. Sci Rep. 2023 Aug 25;13(1):13907.
Molecular Weight
– 434.49
SMILES
– O=S(C(C=C1)=CC=C1N=C2SC3=NC4=CC=CC=C4N=C3N2)(NC5=CC=CC=N5)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– VEGFR
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
