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Products Details
Product Description
– VEGFR-2-IN-28 (compound 12c) is a potent VEGFR-2 inhibitor with IC50 value of 0.83 µM. VEGFR-2-IN-28 induces apoptosis and has anticancer activity[1].
Web ID
– HY-147926
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C26H17N7O7
References
– [1]Dawood DH, et al. Synthesis and molecular docking study of new pyrazole derivatives as potent anti-breast cancer agents targeting VEGFR-2 kinase. Bioorg Chem. 2020 Aug;101:103916.
CAS Number
– 2447597-39-7
Molecular Weight
– 539.46
SMILES
– O=C(N(C1=CC=C([N+]([O-])=O)C=C1[N+]([O-])=O)N=C/2C)C2=CC3=CN(C4=CC=CC=C4)N=C3C5=CC=CC([N+]([O-])=O)=C5
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Apoptosis;VEGFR
Isoform
– VEGFR2/KDR/Flk-1
Pathway
– Apoptosis;Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
