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Products Details
Product Description
– VEGFR-2-IN-21 (Compound 5d) is a potent VEGFR-2 inhibitor with an IC50 of 0.10 μM. VEGFR-2-IN-21 shows anticancer activity[1].
Web ID
– HY-147800
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C28H24ClN7O3S
References
– [1]Saleh NM, et al. Design, green synthesis, molecular docking and anticancer evaluations of diazepam bearing sulfonamide moieties as VEGFR-2 inhibitors. Bioorg Chem. 2020 Nov;104:104350.
CAS Number
– 2531029-88-4
Molecular Weight
– 574.05
SMILES
– O=S(C1=CC=C(/N=N/C2=CC=C(C3=NCC(N(C)C4=CC=C(Cl)C=C34)=O)C=C2)C=C1)(NC5=NC(C)=CC(C)=N5)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– VEGFR
Isoform
– VEGFR2/KDR/Flk-1
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
