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Products Details
Product Description
– VEGFR-2-IN-15 (Compound 14b) is a potent VEGFR-2 inhibitor. VEGFR-2-IN-15 arrests the HepG2 cell growth at the Pre-G1 phase and induces apoptosis[1].
Web ID
– HY-144796
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C23H18ClN3O4S
References
– [1]Elkady H, et al. New benzoxazole derivatives as potential VEGFR-2 inhibitors and apoptosis inducers: design, synthesis, anti-proliferative evaluation, flowcytometric analysis, and in silico studies. J Enzyme Inhib Med Chem. 2022 Dec;37(1):397-410.
Molecular Weight
– 467.92
SMILES
– O=C(NC1=CC=CC=C1OC)C2=CC=C(NC(CSC3=NC4=CC(Cl)=CC=C4O3)=O)C=C2
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Apoptosis;VEGFR
Isoform
– VEGFR2/KDR/Flk-1
Pathway
– Apoptosis;Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
