Products Details

Product Description

– VEGFR-2-IN-14 (Compound 5) is a potent VEGFR-2 inhibitor. VEGFR-2-IN-14 arrests the HepG2 cell growth at the Pre-G1 phase and induces apoptosis[1].

Web ID

– HY-144795

Shipping

– Room temperature

Applications

– Cancer-Kinase/protease

Molecular Formula

– C24H23N3O3S

References

– [1]Hagras M, et al. 1,3,4-Oxadiazole-naphthalene hybrids as potential VEGFR-2 inhibitors: design, synthesis, antiproliferative activity, apoptotic effect, and in silico studies. J Enzyme Inhib Med Chem. 2022 Dec;37(1):380-396.

Molecular Weight

– 433.52

SMILES

– COC1=CC=C2C=C(C=CC2=C1)[C@@H](C3=NN=C(O3)SCC(NCC4=CC=CC=C4)=O)C

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– Apoptosis;VEGFR

Isoform

– VEGFR2/KDR/Flk-1

Pathway

– Apoptosis;Protein Tyrosine Kinase/RTK

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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