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Products Details
Product Description
– VEGFR-2-IN-10 exhibits increased antiangiogenic potency (IC50 = 0.7 μM) against VEGF-induced VEGFR2 phosphorylation without cytotoxic effects.
Web ID
– HY-139822
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C20H21N3O2
References
– [1]Cho SM, et al. Development of Novel VEGFR2 Inhibitors Originating from Natural Product Analogues with Antiangiogenic Impact. J Med Chem. 2021 Nov 11;64(21):15858-15867.
CAS Number
– 2760792-40-1
Molecular Weight
– 335.40
SMILES
– COC1=CC2=C(NC3=C2CN(C(CC4=NC=CC=C4)=O)CCC3)C=C1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– VEGFR
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
