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Products Details
Product Description
– VEGFR-2/c-Met-IN-1 is a dual inhibitoe of VEGFR-2 and c-Met with IC50s of 138 nM and 74 nM, respectively. VEGFR-2/c-Met-IN-1 has antitumor activity[1].
Web ID
– HY-149674
Shipping
– Room temperature
Molecular Formula
– C23H16N4O5S
References
– [1]Abdelfattah Hassan, et al. Novel 3-phenylquinazolin-2,4(1H,3H)-diones as dual VEGFR-2/c-Met-TK inhibitors: design, synthesis, and biological evaluation.Sci Rep. 2023 Oct 30;13(1):18567.
Molecular Weight
– 460.46
SMILES
– O=C(O)C1=CC=C(NC(NC(C2=CC=C(N3C(NC4=C(C=CC=C4)C3=O)=O)C=C2)=O)=S)C=C1
Clinical Information
– No Development Reported
Research Area
– cancer
Solubility
– 10 mM in DMSO
Target
– VEGFR
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
