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Products Details
Product Description
– Vazegepant is the first intranasal CGRP receptor antagonist for the study the acute research of migraine[1][2].
Web ID
– HY-134992
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C36H46N8O3
References
– [1]Leonard KA, et al. Discovery of a Gut-Restricted JAK Inhibitor for the Treatment of Inflammatory Bowel Disease. J Med Chem. 2020 Mar 26;63(6):2915-2929.|[2]Gene M Dubowchik,Charles M Conway,Alison W Xin.Blocking the CGRP Pathway for Acute and Preventive Treatment of Migraine: The Evolution of Success.
CAS Number
– 1337918-83-8
Molecular Weight
– 638.80
SMILES
– O=C(N1CCC(C2=CC3=C(NC2=O)C=CC=C3)CC1)N[C@H](CC4=CC5=C(NN=C5)C(C)=C4)C(N6CCN(C7CCN(C)CC7)CC6)=O
Clinical Information
– Phase 3
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– CGRP Receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
