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Products Details
Product Description
– Vasopressin V2 receptor antagonist 1 (Compound 4g) is a vasopressin V2 receptor (V2R) antagonist with a Ki of 3.8 nM. Vasopressin V2 receptor antagonist 1 can be used for autosomal dominant polycystic kidney disease (ADPKD) research[1].
Web ID
– HY-146272
Shipping
– Room temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C33H37ClN4O4
References
– [1]Haoran Zhang, et al. Long Residence Time at the Vasopressin V2 Receptor Translates into Superior Inhibitory Effects in Ex Vivo and In Vivo Models of Autosomal Dominant Polycystic Kidney Disease. J Med Chem. 2022 Apr 1.
CAS Number
– 2648650-50-2
Molecular Weight
– 589.12
SMILES
– ClC1=CC2=C(C=C1)N(C(C3=C(C=C(C=C3)NC(C4=C(C=CC=C4)C)=O)C)=O)CCCC2NCCC(N5CCOCC5)=O
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– 10 mM in DMSO
Target
– Vasopressin Receptor
Isoform
– V2 ReceptorÂ
Pathway
– GPCR/G Protein
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
