Download Files:
Products Details
Product Description
– Valopicitabine (NM283) is a nucleoside analog and the orally bioavailable proagent of the potent anti-HCV agent 2′-C-methylcytidine (NM107). NM107competitively inhibits NS5B polymerase, causing chain termination[1][2].
Web ID
– HY-108060
Shipping
– Room temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C15H24N4O6
References
– [1]Pierra C, et al. Nm 283, an efficient prodrug of the potent anti-HCV agent 2′-C-methylcytidine. Nucleosides Nucleotides Nucleic Acids. 2005;24(5-7):767-70.|[2]Pierra C, et al. Synthesis and pharmacokinetics of valopicitabine (NM283), an efficient prodrug of the potent anti-HCV agent 2′-C-methylcytidine. J Med Chem. 2006 Nov 2;49(22):6614-20.
CAS Number
– 640281-90-9
Molecular Weight
– 356.37
SMILES
– C[C@@]1([C@@](N2C(N=C(C=C2)N)=O)([H])O[C@@H]([C@H]1OC([C@@H](N)C(C)C)=O)CO)O
Clinical Information
– Phase 2
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– HCV;HCV Protease;Nucleoside Antimetabolite/Analog
Pathway
– Anti-infection;Cell Cycle/DNA Damage;Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
