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VAL-083
$242 – $1,200
Products Details
Product Description
– VAL-083 is an alkylating agent that creates N7 methylation on DNA, with antitumor activity.
Web ID
– HY-16513
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C6H10O4
References
– [1]Kaiji Hu, et al. Abstract 811: VAL083, a novel N7 alkylating agent, surpasses NSC 362856 activity and inhibits cancer stem cells providing a new potential treatment option for glioblastoma multiforme. Cancer Research. 2012 Mar 31-Apr 4.|[2]Jiang X, et al. Dianhydrogalactitol, a potential multitarget agent, inhibits glioblastoma migration, invasion, and angiogenesis. Biomed Pharmacother. 2017 Jul;91:1065-1074.|[3]Peng C, et al. 1,2:5,6-dianhydrogalactitol inhibits human glioma cell growth in vivo and in vitro by arresting the cell cycle at G2/M phase. Acta Pharmacol Sin. 2017 Apr;38(4):561-570.
CAS Number
– 23261-20-3
Molecular Weight
– 146.14
Compound Purity
– 98.0
SMILES
– O[C@H]([C@H](O)[C@]1(OC1)[H])[C@@]2([H])CO2
Clinical Information
– Launched
Research Area
– Cancer
Solubility
– DMF : ≥ 100 mg/mL|DMSO : 200 mg/mL (ultrasonic;warming;heat to 60°C)|H2O : 50 mg/mL (ultrasonic)
Target
– DNA Alkylator/Crosslinker
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
