Products Details

Product Description

– UU-T01 is a selective inhibitor for β-Catenin/T-cell factor 4 protein-protein interaction (β-catenin/Tcf PPI) with an Ki value of 3.14 µM. UU-T01 is directly combined with β-catenin, and the KD value is 0.531 µM[1].

Web ID

– HY-122649

Shipping

– Room temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C10H10N6O

References

– [1]Guo W, et al. Hot spot-based design of small-molecule inhibitors for protein-protein interactions. Bioorg Med Chem Lett. 2014 Jun 1;24(11):2546-54. |[2]Cui C, et al. Is β-catenin a druggable target for cancer therapy?[J]. Trends in biochemical sciences, 2018, 43(8): 623-634.

CAS Number

– 1417162-83-4

Molecular Weight

– 230.23

SMILES

– ON1N=CC2=C1C=CC(CCC3=NNN=N3)=C2

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– β-catenin

Pathway

– Stem Cell/Wnt

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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