USP8-IN-3

SKU HY-149902-10 mg Category Tags , ,

$130$1,100

Products Details

Product Description

– USP8-IN-3 (Compd U51) is a deubiquitinase USP8 inhibitor with an IC50 value of 4.0 μM. USP8-IN-3 also inhibits the proliferation of GH3 and H1957 cells with GI50s of 37.03 μM and 6.01 μM, respectively[1].

Web ID

– HY-149902

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Molecular Formula

– C18H18F3N5O2S

References

– [1]Li zhiyun, et al. Preparing method and application of USP8 inhibitor: China, CN111138358 A. 2020-05-12.

CAS Number

– 2477651-10-6

Molecular Weight

– 425.43

Compound Purity

– 99.17

SMILES

– [O-][N+](C1=CC=C(NC(NC2CCN(CC2)C3=CC=CC(C(F)(F)F)=N3)=S)C=C1)=O

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– DMSO : 100 mg/mL (ultrasonic)

Target

– Deubiquitinase

Isoform

– USP8

Pathway

– Cell Cycle/DNA Damage

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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