USP8-IN-2

$315

Only 1000 item(s) left in stock.

Products Details

Product Description

– USP8-IN-2 (Compd U52) is a deubiquitinase USP8 inhibitor with an IC50 value of 6.0 μM. USP8-IN-2 also inhibits the proliferation of H1957 cells with an GI50 value of 24.93 μM, respectively[1].

Web ID

– HY-149901

Shipping

– Room temperature

Molecular Formula

– C19H20ClF3N4OS

References

– [1]Li zhiyun, et al. Preparing method and application of USP8 inhibitor: China, CN111138358 A. 2020-05-12.

CAS Number

– 2477651-11-7

Molecular Weight

– 444.90

SMILES

– FC(F)(C1=NC(N2CCC(CC2)NC(NC3=CC(Cl)=CC=C3OC)=S)=CC=C1)F

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– Deubiquitinase

Isoform

– USP8

Pathway

– Cell Cycle/DNA Damage

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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