USP7-IN-7

SKU HY-136910-1 mg Category Tags , ,

$466$9,230

Products Details

Product Description

– USP7-IN-7 (compound 124) is a USP7 inhibitor with an IC50 value <10 nM. USP7-IN-7 shows cytotoxicity against p53-mutant cancer cell lines, p53 wild-type blood cancer and neuroblastoma cell lines with low nanomolar values. USP7-IN-7 can be used for cancer research[1].

Web ID

– HY-136910

Storage Temperature

– 4°C (Powder, protect from light)

Shipping

– Room Temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C27H28ClN3O3S

References

– [1]Biannic, Berenger, et al. UBIQUITIN-SPECIFIC-PROCESSING PROTEASE 7 (USP7) MODULATORS AND USES THEREOF. US20200095260. 2019.

CAS Number

– 2413944-70-2

Molecular Weight

– 510.05

Compound Purity

– 97.53

SMILES

– O=C(N1CC2=CC3=NC=CC(C4=CC(Cl)=CC(C)=C4C[C@@H]5CNCCO5)=C3S2)C6C(C)(C)C6C1=O

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– DMSO : 75 mg/mL (ultrasonic;warming;heat to 60°C)

Target

– Deubiquitinase

Pathway

– Cell Cycle/DNA Damage

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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