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USP1-IN-2
$950 – $4,900
Products Details
Product Description
– USP1-IN-2 (Compound I-193) is a potent ubiquitin-specific protease 1 (USP1) inhibitor with an IC50 of less than about 50 nM[1].
Web ID
– HY-148099
Storage Temperature
– -20°C, 3 years (Powder)
Shipping
– Blue Ice
Applications
– Cancer-programmed cell death
Molecular Formula
– C26H22F4N6O
References
– [1]Alexandre Joseph Buckmelter, et al. Purinones as ubiquitin-specific protease 1 inhibitors. Patent US20170145012A1.
CAS Number
– 2098212-05-4
Molecular Weight
– 510.49
Compound Purity
– 99.76
SMILES
– O=C1NC2=CN=C(C3=C(C(C)C)C(F)=CC=C3)N=C2N1CC4=CC=C(C5=NC(C(F)(F)F)=CN5C)C=C4
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 62.5 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– Deubiquitinase
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.