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Urease-IN-2
Products Details
Product Description
– Urease-IN-2 (compound 8g) is a non-competitive urease inhibitor with an IC50 of 0.94 μM and a Ki of 1.6 μM. Urease-IN-2 inhibits the Jack bean urease (JBU) in a non-competitive manner[1].
Web ID
– HY-115939
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C26H25N5O5S3
References
– [1]Mehdi Asadi, et al. Synthesis and in vitro urease inhibitory activity of 5-nitrofuran-2-yl-thiadiazole linked to different cyclohexyl-2-(phenylamino)acetamides, in silico and kinetic studies. Bioorg Chem. 2022 Jan 17;120:105592.
Molecular Weight
– 583.70
SMILES
– O=C(C(N(C1=CC=CC=C1)C(CSC2=NN=C(S2)C3=CC=C(O3)[N+]([O-])=O)=O)C4=CC=CS4)NC5CCCCC5
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Bacterial
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.