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Products Details
Product Description
– UR-MB108 (Compound 57) is a potent, selective ABCG2 (BCRP) inhibitor with an IC50 of 79 nM. UR-MB108 is stable in blood plasma[1].
Web ID
– HY-146676
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C40H38N6O4
References
– [1]Frauke Antoni, et al. Tariquidar-related triazoles as potent, selective and stable inhibitors of ABCG2 (BCRP). Eur J Med Chem. 2020 Apr 1;191:112133.
CAS Number
– 2412461-98-2
Molecular Weight
– 666.77
SMILES
– CCC(C1=CC=C(C=C1NC(C2=NC3=C(C=C2)C=CC=C3)=O)C4=CN(N=N4)C5=CC=C(C=C5)CCN6CCC7=C(C6)C=C(C(OC)=C7)OC)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– BCRP
Pathway
– Membrane Transporter/Ion Channel
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
